FEN1

Description flap structure-specific endonuclease 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31959851 31619474)
  • Bipolar disorder ( 28115744 31043756)
  • Bipolar I disorder ( 31043756)
  • Brain morphology (MOSTest) ( 32665545)
  • Colorectal cancer ( 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Crohn's disease ( 28067908)
  • Delta-5 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Hemoglobin levels ( 32327693)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Male-pattern baldness ( 28196072)
  • Metabolite levels ( 23823483 23378610)
  • Oleic acid (18:1n-9) levels ( 23362303)
  • Palmitoleic acid (16:1n-7) levels ( 23362303)
  • Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377)
  • Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377)
  • Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377)
  • Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
  • Platelet count ( 22139419)
  • QT interval ( 29874175)
  • Red blood cell fatty acid levels ( 25500335)
  • Refractive error ( 32231278)
  • Resting heart rate ( 27798624)
  • Serum metabolite levels ( 23093944)
  • Serum metabolite ratios in chronic kidney disease ( 29545352)
  • Stearic acid (18:0) levels ( 23362303)
Interacting Genes 18 interacting genes: APEX1 APP ARHGDIA BLM CCNA2 CDK1 CDK2 EEF1G EP300 GSK3B HNRNPA1 HUS1 PCNA RAD1 RAD9A TERF1 WDR4 WRN
Entrez ID 2237
HPRD ID 02670
Ensembl ID ENSG00000168496
Uniprot IDs P39748 Q6FHX6
PDB IDs 1U7B 1UL1 3Q8K 3Q8L 3Q8M 3UVU 5E0V 5FV7 5K97 5KSE 5UM9 5ZOD 5ZOE 5ZOF 5ZOG 6TNZ
Enriched GO Terms of Interacting Partners?
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