FECH

Description		ferrochelatase
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Ferrochelatase Activity Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Heme Biosynthetic Process Response To Light Stimulus Response To Lead Ion Response To Insecticide Response To Drug Response To Ethanol Protoporphyrinogen IX Metabolic Process Response To Arsenic-containing Substance Response To Methylmercury Response To Platinum Ion Cellular Response To Dexamethasone Stimulus
Pathways		Heme biosynthesis
Drugs		Cholic Acid Cholic Acid
Diseases		Erythropoietic porphyria (EP), including: Erythropoietic protoporphyria (EPP); Congenital erythropoietic porphyria (CEP); Gunther Disease; X-linked erythropoietic protoporphyria (XLEPP)
GWAS		Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Migraine ( 27182965) Red cell distribution width ( 32888494)
Novel Interacting Genes		1 novel interacting genes: DCC
Interacting Genes		2 interacting genes: ABCB7 ATM
Entrez ID		2235
HPRD ID		01509
Ensembl ID		ENSG00000066926
Uniprot IDs		A0A499FJN5 P22830 Q7KZA3
PDB IDs		1HRK 2HRC 2HRE 2PNJ 2PO5 2PO7 2QD1 2QD2 2QD3 2QD4 2QD5 3AQI 3HCN 3HCO 3HCP 3HCR 3W1W 4F4D 4KLA 4KLC 4KLR 4KMM 4MK4
Enriched GO Terms of Interacting Partners?
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