KDM1B

Description		lysine demethylase 1B
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GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Transcription Factor Binding Zinc Ion Binding Oxidoreductase Activity Histone Demethylase Activity (H3-dimethyl-K4 Specific) Histone Demethylase Activity (H3-monomethyl-K4 Specific) Histone Binding Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression By Genetic Imprinting Multicellular Organism Development Protein Deubiquitination Histone H3-K4 Demethylation Regulation Of DNA Methylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HDMs demethylate histones UCH proteinases NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015)
Interacting Genes		2 interacting genes: H3-4 UBE2D3
Entrez ID		221656
HPRD ID		18524
Ensembl ID		ENSG00000165097
Uniprot IDs		H0Y6H0 Q8NB78
PDB IDs		4FWE 4FWF 4FWJ 4GU0 4GU1 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25
Enriched GO Terms of Interacting Partners?
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