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EPHA8

Description EPH receptor A8
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Early Endosome Membrane
  • Neuron Projection
  • Receptor Complex
Molecular Function
  • Transmembrane Receptor Protein Tyrosine Kinase Activity
  • GPI-linked Ephrin Receptor Activity
  • Transmembrane-ephrin Receptor Activity
  • ATP Binding
Biological Process
  • Substrate-dependent Cell Migration
  • Cell Adhesion
  • Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
  • Multicellular Organism Development
  • Axon Guidance
  • Neuron Remodeling
  • Peptidyl-tyrosine Phosphorylation
  • Regulation Of Cell Adhesion
  • Neuron Projection Development
  • Regulation Of Cell Adhesion Mediated By Integrin
  • Positive Regulation Of Kinase Activity
  • Positive Regulation Of MAPK Cascade
  • Positive Regulation Of Phosphatidylinositol 3-kinase Activity
  • Protein Autophosphorylation
  • Ephrin Receptor Signaling Pathway
  • Cellular Response To Follicle-stimulating Hormone Stimulus
Pathways
  • EPH-Ephrin signaling
  • EPH-Ephrin signaling
  • EPHA-mediated growth cone collapse
  • EPHA-mediated growth cone collapse
  • EPH-ephrin mediated repulsion of cells
  • EPH-ephrin mediated repulsion of cells
Drugs
  • Fostamatinib
Diseases
GWAS
Interacting Genes 12 interacting genes: AK4 DARS2 EFNA1 EFNA4 EFNA5 FYN G3BP1 LRRK1 PIK3CG PSMC5 PTPRD ZNF746
Entrez ID 2046
HPRD ID 01493
Ensembl ID ENSG00000070886
Uniprot IDs P29322
PDB IDs 1UCV 1X5L 3KUL
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025