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ELAVL1

Description ELAV like RNA binding protein 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Endoplasmic Reticulum
  • Cytosol
  • Cytoplasmic Stress Granule
  • Membrane
  • Postsynapse
  • Glutamatergic Synapse
  • Ribonucleoprotein Complex
Molecular Function
  • RNA Binding
  • Double-stranded RNA Binding
  • MRNA Binding
  • MRNA 3'-UTR Binding
  • Protein Binding
  • Protein Kinase Binding
  • MiRNA Binding
  • MRNA 3'-UTR AU-rich Region Binding
  • Protein Homodimerization Activity
Biological Process
  • MRNA Splicing, Via Spliceosome
  • Protein Import Into Nucleus
  • Posttranscriptional Gene Silencing
  • Regulation Of MRNA Stability
  • Positive Regulation Of Translation
  • MRNA Stabilization
  • Protein Homooligomerization
  • Negative Regulation Of Gene Silencing By MiRNA
  • 3'-UTR-mediated MRNA Stabilization
  • Regulation Of Stem Cell Population Maintenance
Pathways
  • HuR (ELAVL1) binds and stabilizes mRNA
  • mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
Novel Interacting Genes 1 novel interacting genes: DNM2
Interacting Genes 37 interacting genes: ANP32A ANP32B APOE C12orf75 CARM1 CELF2 CHEK2 CTNNB1 ERG FAF2 GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VCP VEGFA XIAP
Entrez ID 1994
HPRD ID 16025
Ensembl ID ENSG00000066044
Uniprot IDs Q15717
PDB IDs 3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025