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S1PR3
Description
sphingosine-1-phosphate receptor 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
G Protein-coupled Receptor Activity
Integrin Binding
Protein Binding
Lipid Binding
Sphingosine-1-phosphate Receptor Activity
Biological Process
Sphingosine-1-phosphate Receptor Signaling Pathway
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Notch Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Anatomical Structure Morphogenesis
Regulation Of Metabolic Process
Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Establishment Of Endothelial Barrier
Pathways
G alpha (i) signalling events
Lysosphingolipid and LPA receptors
Extra-nuclear estrogen signaling
Drugs
Fingolimod
Diseases
GWAS
Cardiometabolic and hematological traits (
27668658
)
Logical memory (delayed recall) in Alzheimer's disease dementia (
29274321
)
Monocyte percentage of white cells (
32888494
27863252
)
Response to statins (LDL cholesterol change) (
22331829
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
6 interacting genes:
COMT
GNA13
GNAI1
GNAQ
GYPB
HTR1A
Entrez ID
1903
HPRD ID
03572
Ensembl ID
ENSG00000213694
Uniprot IDs
Q99500
PDB IDs
Enriched GO Terms of Interacting Partners
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