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DUT

Description deoxyuridine triphosphatase
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Mitochondrion
  • Cytosol
  • Extracellular Exosome
Molecular Function
  • Magnesium Ion Binding
  • RNA Binding
  • DUTP Diphosphatase Activity
  • Protein Binding
  • Receptor Inhibitor Activity
  • Pyrimidine Deoxyribonucleotide Binding
  • Identical Protein Binding
  • Peroxisome Proliferator Activated Receptor Binding
Biological Process
  • Liver Development
  • Nucleobase-containing Compound Metabolic Process
  • DUMP Biosynthetic Process
  • DNA Replication
  • Response To Organic Cyclic Compound
  • Nucleobase-containing Small Molecule Interconversion
  • Regulation Of Protein-containing Complex Assembly
  • DUTP Catabolic Process
  • Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs
  • Deoxyuridine-5'-Diphosphate
  • 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Height ( 31562340)
  • Protein quantitative trait loci ( 18464913)
  • Skin pigmentation ( 28300201)
Interacting Genes 9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2
Entrez ID 1854
HPRD ID 03165
Ensembl ID ENSG00000128951
Uniprot IDs A0A0C4DGL3 H0YNW5 P33316
PDB IDs 1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025