DDC

Description		dopa decarboxylase
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GO Annotations	Cellular Component	Cytoplasm Cytosol Synaptic Vesicle Axon Neuronal Cell Body Extracellular Exosome
	Molecular Function	Aromatic-L-amino-acid Decarboxylase Activity Protein Binding Amino Acid Binding Carboxy-lyase Activity Enzyme Binding Protein Domain Specific Binding Pyridoxal Phosphate Binding L-dopa Decarboxylase Activity
	Biological Process	Cellular Amino Acid Metabolic Process Catecholamine Metabolic Process Circadian Rhythm Multicellular Organism Aging Aminergic Neurotransmitter Loading Into Synaptic Vesicle Isoquinoline Alkaloid Metabolic Process Cellular Response To Drug Dopamine Biosynthetic Process Catecholamine Biosynthetic Process Serotonin Biosynthetic Process Indolalkylamine Biosynthetic Process Response To Pyrethroid Phytoalexin Metabolic Process Cellular Response To Alkaloid Cellular Response To Growth Factor Stimulus
Pathways		Catecholamine biosynthesis Serotonin and melatonin biosynthesis
Drugs		Pyridoxal phosphate Carbidopa Methyldopa Benserazide
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464 23512250 19684603) Adult body size ( 32376654) Blood metabolite ratios ( 24816252) Body mass index ( 26426971 25673413) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Chronotype ( 30696823) Malaria ( 19465909) Morning person ( 30696823) Schizophrenia (treatment resistant) ( 25223841)
Interacting Genes		3 interacting genes: AR ATF6 RELA
Entrez ID		1644
HPRD ID		00145
Ensembl ID		ENSG00000132437
Uniprot IDs		A0A087WV24 A0A0S2Z3N4 P20711 Q53Y41
PDB IDs		3RBF 3RBL 3RCH
Enriched GO Terms of Interacting Partners?
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