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DBH
Description
dopamine beta-hydroxylase
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Endoplasmic Reticulum
Membrane
Integral Component Of Membrane
Transport Vesicle Membrane
Secretory Granule Membrane
Centriolar Satellite
Chromaffin Granule Lumen
Secretory Granule Lumen
Chromaffin Granule Membrane
Intracellular Membrane-bounded Organelle
Synapse
Molecular Function
Catalytic Activity
Dopamine Beta-monooxygenase Activity
Copper Ion Binding
Protein Binding
L-ascorbic Acid Binding
Biological Process
Blood Vessel Remodeling
Response To Amphetamine
Leukocyte Mediated Immunity
Octopamine Biosynthetic Process
Chemical Synaptic Transmission
Memory
Locomotory Behavior
Visual Learning
Regulation Of Cell Population Proliferation
Homoiothermy
Dopamine Catabolic Process
Norepinephrine Biosynthetic Process
Catecholamine Biosynthetic Process
Glucose Homeostasis
Fear Response
Maternal Behavior
Positive Regulation Of Vasoconstriction
Behavioral Response To Ethanol
Response To Pain
Leukocyte Migration
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Catecholamine biosynthesis
Drugs
Ascorbic acid
Disulfiram
Dopamine
Diseases
Dopamine beta-hydroxylase deficiency; Norepinephrine deficiency; Noradrenaline deficiency
GWAS
Diastolic blood pressure (
28739976
27618452
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Mean arterial pressure (
27618448
)
Nicotine dependence (
28972577
)
Post bronchodilator FEV1 (
26634245
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Smoking behavior (
20418890
)
Smoking behaviour (cigarette pack-years) (
30679032
)
Smoking behaviour (cigarettes smoked per day) (
30679032
)
Smoking cessation (
30617275
)
Squamous cell lung carcinoma (
28604730
)
Systolic blood pressure (
27618452
30578418
)
Interacting Genes
3 interacting genes:
NBPF19
NOTCH2NLA
PRADC1
Entrez ID
1621
HPRD ID
01963
Ensembl ID
ENSG00000123454
Uniprot IDs
P09172
PDB IDs
4ZEL
Enriched GO Terms of Interacting Partners
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