ADRA2B

Description		adrenoceptor alpha 2B
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle
	Molecular Function	G Protein-coupled Receptor Activity Alpha2-adrenergic Receptor Activity Protein Binding Epinephrine Binding
	Biological Process	Activation Of MAPK Activity Regulation Of Vascular Associated Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Female Pregnancy Negative Regulation Of Norepinephrine Secretion Platelet Activation Activation Of Protein Kinase B Activity Negative Regulation Of Epinephrine Secretion Receptor Transactivation Positive Regulation Of MAPK Cascade Positive Regulation Of Neuron Differentiation Positive Regulation Of Blood Pressure Positive Regulation Of Uterine Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways		Adrenoceptors Adrenaline signalling through Alpha-2 adrenergic receptor G alpha (i) signalling events G alpha (z) signalling events
Drugs		Amphetamine Tramadol Bethanidine Ziprasidone Cabergoline Ropinirole Etomidate Clozapine Norepinephrine Phenylpropanolamine Loxapine Prochlorperazine Prazosin Chlorpromazine Brimonidine Haloperidol Nortriptyline Amoxapine Clonidine Lisuride Guanabenz Epinephrine Tizanidine Apomorphine Paroxetine Trimipramine Risperidone Tolazoline Fenoldopam Phenoxybenzamine Maprotiline Oxymetazoline Apraclonidine Guanfacine Ergoloid mesylate Promethazine Carvedilol Desipramine Escitalopram Pergolide Bromocriptine Quetiapine Aripiprazole Paliperidone Ephedra sinica root Mephentermine Yohimbine Methotrimeprazine Dextroamphetamine Metamfetamine Celiprolol Dronedarone Rotigotine OPC-28326 Epicept NP-1 Mianserin Pizotifen Asenapine Ocaperidone Droxidopa Esmirtazapine Xylometazoline Levonordefrin Dosulepin Etoperidone Lorpiprazole Cirazoline Moxisylyte Aranidipine Setiptiline Racepinephrine Dihydroergocornine DL-Methylephedrine Xylazine Indigotindisulfonic acid Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)
Novel Interacting Genes		1 novel interacting genes: ADAMTS1
Interacting Genes		8 interacting genes: EIF2B1 GGA1 GGA2 GGA3 GNAI2 PPP1R9B UCHL1 YWHAZ
Entrez ID		151
HPRD ID		00086
Ensembl ID		ENSG00000274286
Uniprot IDs		P18089
PDB IDs		2CVA 6K41 6K42
Enriched GO Terms of Interacting Partners?
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