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CRP
Description
C-reactive protein
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Molecular Function
Complement Component C1q Complex Binding
Calcium Ion Binding
Protein Binding
Low-density Lipoprotein Particle Binding
Choline Binding
Identical Protein Binding
Virion Binding
Low-density Lipoprotein Particle Receptor Binding
Biological Process
Acute-phase Response
Inflammatory Response
Complement Activation, Classical Pathway
Opsonization
Positive Regulation Of Gene Expression
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Negative Regulation Of Lipid Storage
Regulation Of Interleukin-8 Production
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Mononuclear Cell Proliferation
Vasoconstriction
Negative Regulation By Host Of Viral Process
Innate Immune Response
Defense Response To Gram-positive Bacterium
Pathways
Classical antibody-mediated complement activation
Drugs
N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium
CRx-139
Diseases
Systemic lupus erythematosus
GWAS
Blood protein levels (
30072576
29875488
23696881
)
C-reactive protein (
22492993
19567438
21647738
18439548
18439552
21196492
23844046
22939635
)
C-reactive protein levels (
24763700
29403010
30388399
21300955
28548082
)
C-reactive protein levels in ischemic stroke (
26718567
)
C-reactive protein levels or triglyceride levels (pleiotropy) (
27286809
)
Inflammatory biomarkers (
22291609
)
Inflammatory biomarkers in Kawasaki disease (
25266886
)
Lung cancer (
18385676
)
Metabolic traits (
19060910
)
Protein quantitative trait loci (
18464913
)
Select biomarker traits (
17903293
)
Interacting Genes
21 interacting genes:
APCS
C1QA
CFH
ESS2
FCGR1A
FCGR2A
FCGR2B
FN1
GLUD1
GMPPA
GP6
H1-1
H2AC16
H2AC20
LAMC3
LEP
MAPK1
MAPK3
MAPK8IP2
RPL13A
SNRNP70
Entrez ID
1401
HPRD ID
00422
Ensembl ID
ENSG00000132693
Uniprot IDs
P02741
PDB IDs
1B09
1CRV
1GNH
1LJ7
3L2Y
3PVN
3PVO
Enriched GO Terms of Interacting Partners
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