MAP4K5

Description		mitogen-activated protein kinase kinase kinase kinase 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Activation Of MAPKKK Activity Protein Phosphorylation Activation Of JUN Kinase Activity Intracellular Signal Transduction
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Cognitive performance ( 20125193) Dupuytren's disease ( 28886342) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 32888494) Periodontal disease-related phenotype (Socransky) ( 24347629) Red blood cell count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: IFT88
Interacting Genes		13 interacting genes: ABL1 BCR COPS5 CRK CRKL GRB2 HCK NEDD4 SETDB1 SMURF1 TANK TRAF2 ZNF440
Entrez ID		11183
HPRD ID		05374
Ensembl ID		ENSG00000012983
Uniprot IDs		B3KWC4 Q9Y4K4
PDB IDs
Enriched GO Terms of Interacting Partners?
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