LILRB1

Description		leukocyte immunoglobulin like receptor B1
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Phosphatase 1 Binding MHC Class Ib Protein Complex Binding MHC Class Ib Protein Binding HLA-A Specific Inhibitory MHC Class I Receptor Activity HLA-B Specific Inhibitory MHC Class I Receptor Activity MHC Class I Receptor Activity MHC Class Ib Receptor Activity SH2 Domain Binding MHC Class I Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Defense Response To Virus By Host Adaptive Immune Response T Cell Proliferation Involved In Immune Response Negative Regulation Of Cytokine Production Involved In Immune Response Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Fc Receptor Mediated Inhibitory Signaling Pathway Signal Transduction Response To Virus Positive Regulation Of Gene Expression Negative Regulation Of Serotonin Secretion Receptor Internalization Interferon-gamma Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Negative Regulation Of Endocytosis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Alpha-beta T Cell Activation Regulation Of Immune Response Defense Response To Virus Negative Regulation Of Calcium Ion Transport Positive Regulation Of Macrophage Cytokine Production Cellular Response To Lipopolysaccharide Negative Regulation Of Transforming Growth Factor Beta Production Dendritic Cell Differentiation Negative Regulation Of Dendritic Cell Apoptotic Process Negative Regulation Of CD8-positive, Alpha-beta T Cell Activation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Gamma-delta T Cell Activation Involved In Immune Response Negative Regulation Of Dendritic Cell Differentiation Negative Regulation Of Osteoclast Development
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		6 interacting genes: B2M HLA-A HLA-B HLA-C HLA-F HLA-G
Entrez ID		10859
HPRD ID		07273
Ensembl ID		ENSG00000104972
Uniprot IDs		A0A087WSV6 A0A087WSX8 A0A0B4J1W1 A8MVE2 D9IDM5 Q8NHL6
PDB IDs		1G0X 1P7Q 1UFU 1UGN 1VDG 3D2U 4LL9 4NO0 5KNM 6AEE 6EWA 6EWC 6EWO 6K60
Enriched GO Terms of Interacting Partners?
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