NFAT5

Description		nuclear factor of activated T cells 5
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cytokine Production Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Response To Osmotic Stress Signal Transduction Excretion Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Cytokine Stimulus Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood osmolality (transformed sodium) ( 28360221) Blood urea nitrogen levels ( 31152163 29403010) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Chloride levels ( 29403010) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 31015462 30604766) Hand grip strength ( 29691431) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Hyperuricemia ( 29124443) Menarche (age at onset) ( 27182965 21102462 25231870) Metabolic syndrome ( 31589552) Pulse pressure ( 28135244 27841878) Self-reported risk-taking behaviour ( 30181555) Serum uric acid levels ( 30993211 29124443) SjÃ¶gren's syndrome ( 28076899) Smoking initiation (ever regular vs never regular) ( 30679032) Sodium levels ( 29403010) Triglyceride levels ( 32154731) Type 2 diabetes ( 30054458 30297969) Urate levels ( 31985003 23263486)
Novel Interacting Genes		1 novel interacting genes: NUTF2
Interacting Genes		3 interacting genes: FOXP3 TBC1D4 TRIM14
Entrez ID		10725
HPRD ID		05272
Ensembl ID		ENSG00000102908
Uniprot IDs		A0A024R734 O94916
PDB IDs		1IMH
Enriched GO Terms of Interacting Partners?
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