CDKN1C

Description		cyclin dependent kinase inhibitor 1C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Kinase Inhibitor Activity Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein-containing Complex Binding
	Biological Process	Cell Cycle Arrest Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Kinase Activity Negative Regulation Of Phosphorylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Kinase Activity
Pathways		Cyclin D associated events in G1 Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
Drugs
Diseases		Beckwith-Wiedemann syndrome Adrenal carcinoma
GWAS		Birth weight ( 31043758) Calcium levels ( 20705733) Malaria ( 31844061)
Novel Interacting Genes		1 novel interacting genes: SLC2A1
Interacting Genes		10 interacting genes: AKT1 CCNE2 CDK4 FBXL12 LIMK1 MYOD1 NR4A2 PCNA RB1 SKP2
Entrez ID		1028
HPRD ID		02913
Ensembl ID		ENSG00000129757
Uniprot IDs		P49918
PDB IDs
Enriched GO Terms of Interacting Partners?
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