ZMPSTE24

Description		zinc metallopeptidase STE24
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GO Annotations	Cellular Component	Nuclear Inner Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Double-stranded DNA Binding Metalloendopeptidase Activity Protein Binding Metalloexopeptidase Activity Metal Ion Binding
	Biological Process	Liver Development Hair Follicle Development Heart Morphogenesis Ventricular Cardiac Muscle Tissue Development Cardiac Ventricle Development Growth Plate Cartilage Development DNA Repair Proteolysis Inflammatory Cell Apoptotic Process Nuclear Envelope Organization Adult Walking Behavior Determination Of Adult Lifespan Regulation Of Cell Shape Regulation Of Autophagy Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Bone Mineralization Prenylated Protein Catabolic Process Regulation Of Bone Mineralization Regulation Of TOR Signaling Regulation Of Hormone Metabolic Process Multicellular Organism Growth Regulation Of Multicellular Organism Growth Maintenance Of RDNA Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Histone H2B-K5 Acetylation Hypomethylation Of CpG Island Cellular Lipid Metabolic Process Regulation Of Fibroblast Proliferation Thymus Development Cardiac Muscle Fiber Development Regulation Of Defense Response To Virus Neuromuscular Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Kidney Morphogenesis Cardiac Conduction CAMKK-AMPK Signaling Cascade Regulation Of Stress-activated Protein Kinase Signaling Cascade Cellular Response To Gamma Radiation CAAX-box Protein Processing Response To DNA Damage Checkpoint Signaling Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Calcium Ion Import Into Sarcoplasmic Reticulum Histone H2A Phosphorylation Regulation Of Histone H4-K16 Acetylation Regulation Of Termination Of RNA Polymerase I Transcription Regulation Of Cellular Senescence
Pathways
Drugs
Diseases		Restrictive dermopathy Mandibuloacral dysplasia
GWAS
Novel Interacting Genes		1 novel interacting genes: PTPRF
Interacting Genes
Entrez ID		10269
HPRD ID		07349
Ensembl ID		ENSG00000084073
Uniprot IDs		O75844
PDB IDs		2YPT 4AW6 5SYT 6BH8
Enriched GO Terms of Interacting Partners?
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