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PLA2G4B
Description
phospholipase A2 group IVB
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Mitochondrial Inner Membrane
Cytosol
Early Endosome Membrane
Molecular Function
Lysophospholipase Activity
Phospholipase A2 Activity
Calcium Ion Binding
Calcium-dependent Phospholipid Binding
Calcium-dependent Phospholipase A2 Activity
Phosphatidyl Phospholipase B Activity
Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
Phospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Inflammatory Response
Parturition
Arachidonic Acid Metabolic Process
Calcium-mediated Signaling
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylserine Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Phosphatidylethanolamine Acyl-chain Remodeling
IRE1-mediated Unfolded Protein Response
Glycerophospholipid Catabolic Process
Pathways
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PG
Hydrolysis of LPC
Synthesis of PA
XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS
Interacting Genes
5 interacting genes:
CASP1
CASP3
CASP7
CASP8
HRAS
Entrez ID
100137049
HPRD ID
Ensembl ID
ENSG00000243708
Uniprot IDs
P0C869
PDB IDs
Enriched GO Terms of Interacting Partners
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