PPP4R1 and PPP4C

Number of citations of the paper that reports this interaction (PubMedID 18715871)
38

Data Source:
HPRD (in vivo, in vitro)

		PPP4R1	PPP4C
Description		protein phosphatase 4 regulatory subunit 1	protein phosphatase 4 catalytic subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase 4 Complex	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Binding Protein Phosphatase Regulator Activity	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Regulation Of Catalytic Activity	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling
Pathways			Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Lean body mass ( 28552196) Metabolite levels ( 23823483) Platelet distribution width ( 27863252)	Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: CEP63 DISC1 HDAC3 PPP4C SASH1	21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6
Entrez ID		9989	5531
HPRD ID		05366	03615
Ensembl ID		ENSG00000154845	ENSG00000149923
Uniprot IDs		Q8TF05	A0A024R625 P60510
PDB IDs
Enriched GO Terms of Interacting Partners?
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