PPP4C and PPP4R1

Number of citations of the paper that reports this interaction (PubMedID 18715871)
38

Data Source:
HPRD (in vivo, in vitro)

		PPP4C	PPP4R1
Description		protein phosphatase 4 catalytic subunit	protein phosphatase 4 regulatory subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex	Protein Phosphatase 4 Complex
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Phosphoprotein Phosphatase Activity Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Regulation Of Catalytic Activity
Pathways		Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)	Lean body mass ( 28552196) Metabolite levels ( 23823483) Platelet distribution width ( 27863252)
Interacting Genes		21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6	5 interacting genes: CEP63 DISC1 HDAC3 PPP4C SASH1
Entrez ID		5531	9989
HPRD ID		03615	05366
Ensembl ID		ENSG00000149923	ENSG00000154845
Uniprot IDs		A0A024R625 P60510	Q8TF05
PDB IDs
Enriched GO Terms of Interacting Partners?
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