NR1I3 and MAP4

Number of citations of the paper that reports this interaction (PubMedID 15604093)
56

Data Source:
HPRD (two hybrid)

		NR1I3	MAP4
Description		nuclear receptor subfamily 1 group I member 3	microtubule associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton	Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Microtubule Cytoskeleton Axon Neuron Projection Mitotic Spindle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Structural Molecule Activity Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Neuron Projection Development Microtubule Sliding Establishment Of Spindle Orientation Cell Division Negative Regulation Of Non-motile Cilium Assembly
Pathways
Drugs		Doxylamine Meclizine Loperamide Ketoconazole Atorvastatin Pheniramine Prasterone 16,17-Androstene-3-Ol Resveratrol Cholesterol Phenolphthalein 3,20-Pregnanedione Hexestrol Triclosan	Paclitaxel Docetaxel Artenimol
Diseases
GWAS		Blood metabolite levels ( 24816252)	Blood pressure ( 21909110) Body mass index and systole blood pressure (pairwise) ( 33619380) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 27841878 28739976 27618452) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean arterial pressure ( 27618448) Medication use (calcium channel blockers) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 28739976 27618452 30578418)
Interacting Genes		19 interacting genes: CHD9 DEDD DNMT3L FTH1 HNF4A IGH MAP4 MED1 NCOA1 NCOA3 NR0B2 POU1F1 PPARGC1A PSMC4 PSMC5 RXRA SNRPD3 SNX13 SRC	23 interacting genes: CCNB1 CDC42 CDK1 CLASP1 ENO2 ERBIN GSK3B IL7R LDLR MARK1 MARK4 NOP58 NR1I3 POT1 RXRB RXRG SNTA1 SRPK2 STRBP SUMO2 TERF1 TUBB UBC
Entrez ID		9970	4134
HPRD ID		04858	01141
Ensembl ID		ENSG00000143257	ENSG00000047849
Uniprot IDs		F1DAL4 Q14994	P27816
PDB IDs		1XV9 1XVP
Enriched GO Terms of Interacting Partners?
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