DHX38 and BCO1

		DHX38	BCO1
Description		DEAH-box helicase 38	beta-carotene oxygenase 1
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome	Cytosol
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity	Beta-carotene 15,15'-dioxygenase Activity Carotenoid Dioxygenase Activity Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Retinoid Metabolic Process Carotene Catabolic Process Vitamin A Biosynthetic Process Retinol Metabolic Process Retinal Metabolic Process Beta-carotene Metabolic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Retinoid metabolism and transport
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		16 interacting genes: AARS1 ACTL7B BCO1 CDC40 CMTM3 CSNK2A1 CTCF E2F4 MFAP1 NDRG4 NOL3 PPP4C SNRNP200 TNFRSF4 U2AF1 WBP4	1 interacting genes: DHX38
Entrez ID		9785	53630
HPRD ID		05720	12042
Ensembl ID		ENSG00000140829	ENSG00000135697
Uniprot IDs		Q92620	Q9HAY6
PDB IDs		5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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