BCO1 and DHX38

		BCO1	DHX38
Description		beta-carotene oxygenase 1	DEAH-box helicase 38
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Beta-carotene 15,15'-dioxygenase Activity Carotenoid Dioxygenase Activity Metal Ion Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Retinoid Metabolic Process Carotene Catabolic Process Vitamin A Biosynthetic Process Retinol Metabolic Process Retinal Metabolic Process Beta-carotene Metabolic Process	MRNA Splicing, Via Spliceosome
Pathways		Retinoid metabolism and transport	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		1 interacting genes: DHX38	16 interacting genes: AARS1 ACTL7B BCO1 CDC40 CMTM3 CSNK2A1 CTCF E2F4 MFAP1 NDRG4 NOL3 PPP4C SNRNP200 TNFRSF4 U2AF1 WBP4
Entrez ID		53630	9785
HPRD ID		12042	05720
Ensembl ID		ENSG00000135697	ENSG00000140829
Uniprot IDs		Q9HAY6	Q92620
PDB IDs			5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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