RUBCN and EXOC1

Number of citations of the paper that reports this interaction (PubMedID 21241894)
137

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RUBCN	EXOC1
Description		rubicon autophagy regulator	exocyst complex component 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		15 interacting genes: ANKRD11 BRD1 BYSL DPF2 ENKD1 EXOC1 FAM161A FAM9B GAS8 NME7 SMAD9 TCEANC VEZF1 ZNF250 ZNF648	29 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIO
Entrez ID		9711	55763
HPRD ID		11069	07615
Ensembl ID		ENSG00000145016	ENSG00000090989
Uniprot IDs		Q8N4U6 Q92622	A0A024RDA1 A1LT29 Q9NV70
PDB IDs		6WCW
Enriched GO Terms of Interacting Partners?
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