EXOC1 and SH3BP5

Number of citations of the paper that reports this interaction (PubMedID 17043677)
193

Data Source:
BioGRID (two hybrid)

		EXOC1	SH3BP5
Description		exocyst complex component 1	SH3 domain binding protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane	Nucleoplasm Cytoplasm Mitochondrion Nuclear Body Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding SH3 Domain Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus	Signal Transduction Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439) Heschl's gyrus morphology ( 25130324) Prudent dietary pattern ( 28644415)
Interacting Genes		29 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIO	16 interacting genes: APP BTK CDC5L DISC1 DST EXOC1 IFT20 MAPK10 MAPK12 MAPK8 MAPK9 NAP1L2 SOS1 SPTBN1 SYNE1 TNKS
Entrez ID		55763	9467
HPRD ID		07615	12030
Ensembl ID		ENSG00000090989	ENSG00000131370
Uniprot IDs		A0A024RDA1 A1LT29 Q9NV70	A0A024R2J3 O60239
PDB IDs			4H3B 6DJL 6IXE 6IXF 6IXG 6IXV
Enriched GO Terms of Interacting Partners?
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