RIN1 and CCM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RIN1	CCM2
Description		Ras and Rab interactor 1	CCM2 scaffold protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Cytoplasm Mitochondrion Protein-containing Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Endocytosis Signal Transduction Regulation Of Catalytic Activity	Vasculogenesis In Utero Embryonic Development Endothelial Cell Development Integrin-mediated Signaling Pathway Multicellular Organism Growth Cell-cell Junction Organization Inner Ear Development Venous Blood Vessel Morphogenesis Stress-activated MAPK Cascade Pericardium Development Blood Vessel Endothelial Cell Differentiation Endothelial Tube Morphogenesis
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1	6 interacting genes: HOXC8 POT1 RIN1 SMURF1 SRPK2 TLNRD1
Entrez ID		9610	83605
HPRD ID		05813	09719
Ensembl ID		ENSG00000174791	ENSG00000136280
Uniprot IDs		A0A0S2Z4U0 Q13671	B7Z8D5 Q9BSQ5
PDB IDs			4FQN 4TVQ 4WJ7 4Y5O 4YKC 4YKD 4YL6
Enriched GO Terms of Interacting Partners?
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