CARTPT and MEIS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CARTPT	MEIS2
Description		CART prepropeptide	Meis homeobox 2
Image
GO Annotations	Cellular Component	Extracellular Space Secretory Granule Synapse	Chromatin Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Neuropeptide Hormone Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cellular Glucose Homeostasis Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Adult Feeding Behavior Cellular Response To Starvation Negative Regulation Of Appetite Positive Regulation Of Epinephrine Secretion Circadian Regulation Of Gene Expression Positive Regulation Of MAPK Cascade Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Bone Resorption Positive Regulation Of Protein Kinase Activity Regulation Of Insulin Secretion Positive Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Glucagon Secretion Somatostatin Secretion	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways
Drugs		Amphetamine
Diseases
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		5 interacting genes: CEACAM1 CEACAM6 MEIS2 MRPS27 SDHB	50 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CHRNA7 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3
Entrez ID		9607	4212
HPRD ID		04006	03443
Ensembl ID		ENSG00000164326	ENSG00000134138
Uniprot IDs		Q16568	A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770
PDB IDs		1HY9	3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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