MEIS2 and RUSC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MEIS2	RUSC1
Description		Meis homeobox 2	RUN and SH3 domain containing 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Perinuclear Region Of Cytoplasm	Nucleus Early Endosome Golgi Apparatus Cytosol Microtubule Postsynaptic Density Microtubule Cytoskeleton Cytoplasmic Vesicle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Actin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation	Protein Polyubiquitination
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		50 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CHRNA7 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3	93 interacting genes: ABHD11 ABHD5 ABI2 AKAP8L ANKS1A APP ATP6V0D2 BPIFA1 C1orf109 CCDC120 CCDC57 CCHCR1 CCNC CDKN2B CMTM6 CREM CRYBA2 CTAG1A CTAG1B DMRT3 DOK6 DPH5 DTX2 DVL2 EXOC8 EXOSC8 FAM9B FNDC3B GCM2 HMG20A HNRNPF INSC KCTD9 KRTAP19-1 KRTAP19-5 KRTAP6-2 KRTAP8-1 LIMS3 LIMS4 LMO2 MAGEA3 MAGEA6 MAGED1 MED25 MEIS2 MISP MOAP1 MORN3 MYOZ3 N4BP3 NICN1 NTAQ1 NTRK1 NUDT22 OIP5 P4HA3 PFDN5 PIK3R3 PLA2G6 PM20D2 PNMA1 POLR1C PRDM14 PRR35 RBPMS SMARCB1 SMYD1 SOHLH1 SPAG8 STUB1 SUOX TBC1D25 TCHP TEKT4 TENT5B TLE5 TRAPPC6A TRIM55 TRIM63 TRIM73 TSSK3 TTC19 TTC7B UFSP1 VGLL3 WWOX WWP2 ZIC1 ZMYND12 ZNF34 ZNF620 ZNF765 ZNF77
Entrez ID		4212	23623
HPRD ID		03443	10206
Ensembl ID		ENSG00000134138	ENSG00000160753
Uniprot IDs		A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770	B4DQB8 Q9BVN2
PDB IDs		3K2A 4XRM 5BNG 5EG0	4GIW
Enriched GO Terms of Interacting Partners?
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