MED27 and ARFGAP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MED27	ARFGAP1
Description		mediator complex subunit 27	ADP ribosylation factor GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytosol Mediator Complex	Golgi Membrane Cytosol Synapse
	Molecular Function	Transcription Coactivator Activity Protein Binding Ubiquitin Protein Ligase Activity	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated	Protein Transport Vesicle-mediated Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Gout (normal type) ( 32238385) Triglyceride levels ( 32203549)
Interacting Genes		11 interacting genes: AFP ARFGAP1 ESR1 FBXO7 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5	36 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GGCX GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SLC6A1 SMN1 TK1 TMED2 TRIM23
Entrez ID		9442	55738
HPRD ID		05438	06443
Ensembl ID		ENSG00000160563	ENSG00000101199
Uniprot IDs		A0A024R8B7 Q6P2C8	Q53F62 Q8N6T3
PDB IDs			3DWD 3O47
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?