UBE4A and SLA

Number of citations of the paper that reports this interaction (PubMedID 24457997)
13

Data Source:
BioGRID (affinity chromatography technology, pull down)

		UBE4A	SLA
Description		ubiquitination factor E4A	Src like adaptor
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm	Endosome Cytosol Focal Adhesion Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Dendritic Spine
	Molecular Function	Protein Binding Ubiquitin-ubiquitin Ligase Activity	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Protein Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Cell Differentiation Innate Immune Response
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Negative regulation of FLT3
Drugs
Diseases
GWAS		Celiac disease and Rheumatoid arthritis ( 26546613) Fat distribution (HIV) ( 21897333)	Bone erosion in rheumatoid arthritis ( 28512992) Brain morphology (MOSTest) ( 32665545) Eosinophil percentage of white cells ( 32888494) Graves' disease ( 23612905) Multiple sclerosis ( 31604244) Temperament ( 22832960) Vitiligo ( 27723757 22561518)
Interacting Genes		14 interacting genes: CASP6 EPHA2 GZMB IP6K1 MAVS PTTG1 RSAD2 SC5D SLA UBE2D1 UBE2D2 UBE2D3 UBE2D4 VCP	22 interacting genes: ABI2 BLK CBL CD247 EGFR EPHA2 ERBB2 ERBB3 ERBB4 FGFR1 FLT3 GAB1 GSK3B LAT MYO15B PAFAH1B2 PTK6 QARS1 SYK UBE4A VAV1 ZAP70
Entrez ID		9354	6503
HPRD ID		06793	03060
Ensembl ID		ENSG00000110344	ENSG00000155926
Uniprot IDs		Q14139	Q13239
PDB IDs		1WGM	2CUD
Enriched GO Terms of Interacting Partners?
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