UBE4A and SC5D

		UBE4A	SC5D
Description		ubiquitination factor E4A	sterol-C5-desaturase
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ubiquitin-ubiquitin Ligase Activity	C-5 Sterol Desaturase Activity Iron Ion Binding Oxidoreductase Activity Delta7-sterol 5(6)-desaturase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway	Lipid Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS		Celiac disease and Rheumatoid arthritis ( 26546613) Fat distribution (HIV) ( 21897333)
Interacting Genes		14 interacting genes: CASP6 EPHA2 GZMB IP6K1 MAVS PTTG1 RSAD2 SC5D SLA UBE2D1 UBE2D2 UBE2D3 UBE2D4 VCP	7 interacting genes: CGREF1 FRMD5 RPS25 SCN4B SLC19A2 UBE4A VGLL1
Entrez ID		9354	6309
HPRD ID		06793	09078
Ensembl ID		ENSG00000110344	ENSG00000109929
Uniprot IDs		Q14139	A0A024R3G4 O75845
PDB IDs		1WGM
Enriched GO Terms of Interacting Partners?
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