TRIP13 and MFGE8

		TRIP13	MFGE8
Description		thyroid hormone receptor interactor 13	milk fat globule EGF and factor V/VIII domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Chromosome	Acrosomal Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent Phosphatidylethanolamine Binding
	Biological Process	Oocyte Maturation Double-strand Break Repair Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Signaling	Angiogenesis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Single Fertilization Apoptotic Cell Clearance Positive Regulation Of Phagocytosis
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation
Drugs
Diseases
GWAS		Pancreatic cancer ( 25086665)	Blood protein levels ( 30072576 29875488 28240269) Coronary artery disease ( 32469254 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Major depressive disorder x sex interaction ( 34099189) Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		113 interacting genes: ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BUB1B C11orf54 C19orf54 C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655	7 interacting genes: LOXL1 MRPL46 MRPS11 PRLR PSTPIP1 TM6SF1 TRIP13
Entrez ID		9319	4240
HPRD ID		05145	03789
Ensembl ID		ENSG00000071539	ENSG00000140545
Uniprot IDs		Q15645	B3KTQ2 B4E396 Q08431
PDB IDs		5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?
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