TRIP13 and METTL15

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		TRIP13	METTL15
Description		thyroid hormone receptor interactor 13	methyltransferase like 15
Image			No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Chromosome	Mitochondrial Matrix
	Molecular Function	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding	RRNA (cytosine-N4-)-methyltransferase Activity
	Biological Process	Oocyte Maturation Double-strand Break Repair Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Signaling	RRNA Base Methylation
Pathways
Drugs
Diseases
GWAS		Pancreatic cancer ( 25086665)	Adventurousness ( 30643258) Body size at age 10 ( 32376654) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Childhood body mass index ( 33045005) Chronotype ( 30696823) Daytime nap ( 33568662) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Intraocular pressure ( 31959993) Major depressive disorder (MTAG) ( 33479212) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27841878) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		113 interacting genes: ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BUB1B C11orf54 C19orf54 C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655	14 interacting genes: CIDEC CSTF2 FANCL GLYCTK HOXC8 MAPKBP1 MSRB3 NEK6 PEF1 PROP1 SPAG8 TRIP13 USHBP1 VAC14
Entrez ID		9319	196074
HPRD ID		05145	08750
Ensembl ID		ENSG00000071539	ENSG00000169519
Uniprot IDs		Q15645	A6NJ78
PDB IDs		5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?
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