GPR37L1 and AQP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPR37L1	AQP10
Description		G protein-coupled receptor 37 like 1	aquaporin 10
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane	Lipid Droplet Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity
	Biological Process	Negative Regulation Of Systemic Arterial Blood Pressure Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Water Transport Response To Toxic Substance Glycerol Transport Protein Homotetramerization Cellular Response To Acidic PH Urea Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Passive transport by Aquaporins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)	Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein level ( 29403010)
Interacting Genes		52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B	20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B
Entrez ID		9283	89872
HPRD ID		13603	07361
Ensembl ID		ENSG00000170075	ENSG00000143595
Uniprot IDs		O60883	Q96PS8
PDB IDs			6F7H
Enriched GO Terms of Interacting Partners?
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