ITGB1BP1 and UTRN

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		ITGB1BP1	UTRN
Description		integrin subunit beta 1 binding protein 1	utrophin
Image
GO Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Membrane Nuclear Body Lamellipodium Centriolar Satellite Perinuclear Region Of Cytoplasm Cell Periphery	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Cell Projection Postsynaptic Membrane Extracellular Exosome Contractile Ring
	Molecular Function	GDP-dissociation Inhibitor Activity Integrin Binding Protein Binding Protein Kinase Binding	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding
	Biological Process	Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Cell-matrix Adhesion Notch Signaling Pathway Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Fibroblast Migration Cell Migration Cell Differentiation Biomineral Tissue Development Negative Regulation Of Protein Binding Activation Of Protein Kinase B Activity Integrin Activation Regulation Of Cell Adhesion Mediated By Integrin Tube Formation Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of GTPase Activity Receptor Clustering Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Myoblast Migration Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Cell Division Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Protein Localization To Plasma Membrane Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of Protein Targeting To Membrane Blood Vessel Diameter Maintenance Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Integrin-mediated Signaling Pathway	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Actin Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 33830993 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Refractive error ( 32231278) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929) Restless legs syndrome in migraine without aura ( 32918390)
Interacting Genes		20 interacting genes: APP CAMK2A CCDC33 DLD DYNC2LI1 EEF1A1 FAF1 FIGNL1 GSDME ITGB1 KRIT1 LRP1 LRP2 LRP8 RHOH SLC35F5 SMO SMURF1 SMURF2 UTRN	22 interacting genes: ACTA1 ACTN2 C1QTNF9 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB ITGB1BP1 MARCHF5 MARK2 NUP98 PGM5 PRKACA PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2
Entrez ID		9270	7402
HPRD ID		06194	00547
Ensembl ID		ENSG00000119185	ENSG00000152818
Uniprot IDs		B4DQY5 O14713	P46939 Q6LBS5
PDB IDs		1K11 4DX8 4DX9 4JIF	1BHD 1QAG 6M5G
Enriched GO Terms of Interacting Partners?
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