DLG5 and BTBD10

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLG5	BTBD10
Description		discs large MAGUK scaffold protein 5	BTB domain containing 10
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Cell Junction Ciliary Basal Body	Fibrillar Center Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Beta-catenin Binding Cytoskeletal Protein Binding Signaling Receptor Complex Adaptor Activity	Protein Binding
	Biological Process	Epithelial To Mesenchymal Transition Signal Transduction Negative Regulation Of Cell Population Proliferation Maintenance Of Cell Polarity Negative Regulation Of Cell Migration Polarized Epithelial Cell Differentiation Midbrain Development Negative Regulation Of Hippo Signaling Positive Regulation Of Hippo Signaling Intracellular Signal Transduction Negative Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Apical Protein Localization Zonula Adherens Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Synapse Assembly Epithelial Tube Branching Involved In Lung Morphogenesis Positive Regulation Of Dendritic Spine Development Protein-containing Complex Assembly Protein Localization To Adherens Junction Metanephric Collecting Duct Development Cell-cell Adhesion	Positive Regulation Of Phosphorylation Type B Pancreatic Cell Proliferation Negative Regulation Of Neuron Death
Pathways		RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874 33339817) Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 33547301 34315874) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 22001757) Macular thickness ( 30535121) Obesity-related traits ( 23251661) Retinal detachment or retinal break ( 31816047) Serum alkaline phosphatase levels ( 33547301)	Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel ( 28935272)
Interacting Genes		8 interacting genes: ABCA1 BTBD10 CD81 CTNNB1 DLST PFN1 SORBS3 TERF1	8 interacting genes: ACIN1 CDC37 CUL3 DLG5 LAMA5 MAPK3 PPP1CA PPP1CC
Entrez ID		9231	84280
HPRD ID		04972	17045
Ensembl ID		ENSG00000151208	ENSG00000148925
Uniprot IDs		Q8TDM6	B7Z503 D3DQW7 Q9BSF8
PDB IDs		1UIT
Enriched GO Terms of Interacting Partners?
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