NEK9 and MBP

Number of citations of the paper that reports this interaction (PubMedID 11864968)
24

Data Source:
HPRD (in vitro)

		NEK9	MBP
Description		NIMA related kinase 9	myelin basic protein
Image
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Nucleus Cytosol Plasma Membrane Cell Surface Protein-containing Complex Internode Region Of Axon Neuronal Cell Body Myelin Sheath Compact Myelin Synapse Cell Periphery
	Molecular Function	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity	Protease Binding Protein Binding Calmodulin Binding Structural Constituent Of Myelin Sheath
	Biological Process	Protein Phosphorylation Cell Cycle Cell Division	MAPK Cascade Immune Response Chemical Synaptic Transmission Central Nervous System Development Sensory Perception Of Sound Axon Ensheathment Response To Toxic Substance Substantia Nigra Development Positive Regulation Of Interleukin-6 Production Negative Regulation Of Heterotypic Cell-cell Adhesion Maintenance Of Blood-brain Barrier Myelination Membrane Organization Positive Regulation Of Metalloendopeptidase Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		Fostamatinib
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)	Age-related macular degeneration (geographic atrophy) ( 22705344) Blood osmolality (transformed sodium) ( 28360221) Depression in smokers ( 30219690) Erythrocyte cadmium concentration in never smokers ( 27005419) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Verbal declarative memory ( 25648963)
Interacting Genes		21 interacting genes: BICD2 CSN2 GABARAP GZMB IFT43 JDP2 LIN52 MALL MAP1LC3B MBP NEK6 NEK7 NEK8 PALS1 RAN RARG RPS6KL1 SSRP1 SUPT16H TTN WDR33	82 interacting genes: ABL1 ADRB2 APTX ATN1 ATXN1 AURKA BMP2K CCR1 CDK1 CDK12 CDK5 CDK7 CDK8 CDK9 CLK1 CTDSP1 CTDSPL DYRK1B HIPK2 HLA-DRA IKBKE ILK IRAK1 IRAK4 LIMK1 LIMK2 LRRK2 MAG MAP2K1 MAP3K1 MAP3K3 MAP3K5 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3 MAPK8 MAPKAPK5 MELK MICU2 MKNK1 MMP7 NEK9 PAK1 PDGFRL PKN1 PLEKHF2 PLP1 PPP2R5C PRKACA PRKCA PRKCB PRKCD PRKCI PRKCZ PRKDC PRMT1 PRMT5 PTAFR PTPRA RAF1 RAN RPS6KA5 RTN4 SQSTM1 SRPK1 STK16 STK26 STK3 STK39 STK4 TBK1 TLK1 TLK2 TRAF6 TRPM7 TSC1 TSSK6 ULK1
Entrez ID		91754	4155
HPRD ID		11386	01158
Ensembl ID		ENSG00000119638	ENSG00000197971
Uniprot IDs		A0A7I2V454 A0A7I2V5R1 Q6PKF2 Q8TD19	A0A024R384 P02686
PDB IDs		3ZKE 3ZKF	1BX2 1FV1 1HQR 1K2D 1QCL 1YMM 1ZGL
Enriched GO Terms of Interacting Partners?
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