CACNA1I and GTPBP1

		CACNA1I	GTPBP1
Description		calcium voltage-gated channel subunit alpha1 I	GTP binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Voltage-gated Calcium Channel Complex Neuron Projection	Cytoplasmic Exosome (RNase Complex) Cytosol Membrane
	Molecular Function	Voltage-gated Calcium Channel Activity Voltage-gated Sodium Channel Activity Protein Binding Low Voltage-gated Calcium Channel Activity	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding
	Biological Process	Signal Transduction Neuronal Action Potential Flagellated Sperm Motility Sleep Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential	Translational Elongation Immune Response Signal Transduction GTP Metabolic Process Positive Regulation Of MRNA Catabolic Process
Pathways		NCAM1 interactions
Drugs		Ergocalciferol Enflurane Amlodipine Spironolactone Cinnarizine Paramethadione Zonisamide Nifedipine Amiodarone Mibefradil Flunarizine Nylidrin Cannabidiol Trimebutine Benidipine Efonidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Hodgkin's lymphoma ( 34216518) Household income (MTAG) ( 31844048) IgG glycosylation ( 23382691) Intelligence (MTAG) ( 29326435) Negative urgency ( 30718321) Refractive error ( 32231278) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Schizophrenia ( 28991256 22883433 29483656 30285260)	Apolipoprotein A1 levels ( 32203549) C-reactive protein levels ( 30388399) Diverticular disease ( 30177863) Hand grip strength ( 29691431) Hip circumference adjusted for BMI ( 34021172) Mean reticulocyte volume ( 32888494) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		11 interacting genes: APOBEC1 APOL1 DNAL4 GTPBP1 HMGXB4 JOSD1 PICK1 PLA2G6 SYNGR1 TST VPS28	5 interacting genes: APP C7orf25 CACNA1I DNAL4 LRP1
Entrez ID		8911	9567
HPRD ID		10500	03765
Ensembl ID		ENSG00000100346	ENSG00000100226
Uniprot IDs		Q9P0X4	O00178
PDB IDs
Enriched GO Terms of Interacting Partners?
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