CBFA2T2 and FBXL19

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		CBFA2T2	FBXL19
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	F-box and leucine rich repeat protein 19
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding	Transcription Coregulator Activity Protein Binding Zinc Ion Binding Histone Demethylase Activity Unmethylated CpG Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Protein Demethylation Histone Demethylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Triglyceride levels ( 32203549)	Diastolic blood pressure ( 28135244 27841878) Mean corpuscular volume ( 27863252) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878)
Interacting Genes		34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PHAF1 PRDM14 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652	12 interacting genes: ABI1 ABI2 CBFA2T2 CREBBP DGAT2L6 EFHC2 NCK2 RPRM SORBS3 TMEM239 TRIM27 TRIM29
Entrez ID		9139	54620
HPRD ID		04721	12366
Ensembl ID		ENSG00000078699	ENSG00000099364
Uniprot IDs		O43439	H3BVB1 Q6PCT2
PDB IDs			6ASB
Enriched GO Terms of Interacting Partners?
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