SEC11C and TMEM128

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SEC11C	TMEM128
Description		SEC11 homolog C, signal peptidase complex subunit	transmembrane protein 128
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cellular_component Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	Molecular_function Protein Binding
	Biological Process	Signal Peptide Processing	Biological_process
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Chronotype ( 30696823) Morning person ( 30696823)	Glomerular filtration rate ( 24351856)
Interacting Genes		23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA	61 interacting genes: AQP6 ARL13B BCL2L13 BEST2 CD40 CD53 CD79A CLDN5 CLDN7 CLN8 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM209A GAD2 GJA1 GJA8 GJB5 GORAB GPR152 GPX8 HSD17B11 IER3IP1 IL3RA JAGN1 KCNK5 LEUTX LHFPL2 LHFPL5 LMNA MAPK8IP2 MFF MFSD5 MRPS18B MTERF1 MTIF3 MUC1 REEP4 RETREG3 SCN3B SEC11C SHISAL1 SLC10A6 SLC18A1 SLC1A3 SLC26A6 SLC34A2 SLC7A14 SSMEM1 STX1A TMEM106A TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 TMX2 ZDHHC15 ZFYVE27
Entrez ID		90701	85013
HPRD ID		15310	17483
Ensembl ID		ENSG00000166562	ENSG00000132406
Uniprot IDs		K7EJQ7 Q9BY50	B7Z3K1 Q5BJH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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