GADD45GIP1 and NR4A1

Number of citations of the paper that reports this interaction (PubMedID 15459248)
19

Data Source:
HPRD (in vivo, two hybrid)

		GADD45GIP1	NR4A1
Description		GADD45G interacting protein 1	nuclear receptor subfamily 4 group A member 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Ribosome	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Mitochondrion Cytosol Nuclear Membrane Presynapse
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Nuclear Receptor Activity Protein Binding Zinc Ion Binding Glucocorticoid Receptor Binding Identical Protein Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Cycle	Positive Regulation Of Endothelial Cell Proliferation Response To Amphetamine Cell Migration Involved In Sprouting Angiogenesis Regulation Of Transcription By RNA Polymerase II Apoptotic Process Signal Transduction Neurotransmitter Secretion Involved In Regulation Of Skeletal Muscle Contraction Intracellular Receptor Signaling Pathway Response To Lipopolysaccharide Endothelial Cell Chemotaxis Skeletal Muscle Cell Differentiation Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Fibroblast Growth Factor Stimulus Fat Cell Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Electrical Stimulus Regulation Of Type B Pancreatic Cell Proliferation Cellular Response To Corticotropin-releasing Hormone Stimulus
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	AKT phosphorylates targets in the nucleus Nuclear Receptor transcription pathway Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		62 interacting genes: ANKRD28 APP AR BPIFA1 CADPS CARD10 CBY2 CCNC CEP70 CSNK2B DVL3 EAF1 ENKD1 EXOSC4 FBXO7 GADD45A GADD45B GADD45G GAS8 GEM GOLGA2 GOLGA6A GOLGA6L9 GPRASP2 HMG20A IKBKG KANK2 KIFC3 KRT27 KRT31 KRT34 KRT40 LDOC1 LRRC73 LZTS2 MAGEA11 MAGEA6 MBD3 MIPOL1 MKRN3 MRPL38 MTUS2 MYG1 MYO15B NFKBID NR4A1 NTAQ1 NUTM1 OIP5 PBX4 PICK1 PNMA1 PRDM6 PSMB1 RBM11 SPTA1 TFIP11 TRAF1 TRIM27 UPF2 WWP2 ZRANB1	88 interacting genes: ABCA5 ABCB11 ABCC13 ABCC6 ABCG8 AKT1 ANKIB1 ARHGEF10L ARHGEF5 ATM ATXN1 BBS10 BCL2 BCL2A1 BCL2L10 CD2AP CDKN2D CHD1L CHD3 CHEK2 CPT1A CUTA DIABLO EP300 ERBB3 FAF1 FXYD3 GADD45GIP1 GK GLOD4 GLUD1 HADHA HES1 HIF1A HNRNPA2B1 HSP90AB1 KAT2B KRTAP10-1 KRTAP10-5 LONRF1 LSS MAP3K1 MAPK1 MAPK8 MED1 MED31 NACAD NCOA1 NCOA2 NCOA3 NCOR2 NDRG1 NFKB1 NR3C1 PGBD1 PML POLA2 PPARG PPBP PPM1A PRDX4 PRDX6 RBL1 ROBO2 RPL7 RPS6KA1 RPS6KA3 RPS6KA5 RPS6KA6 RTN4 RXRA RXRG SERPINA4 SERPING1 SMAD3 SOCS4 STAT3 SUGT1 TCF4 TP53 TRAF2 TRIM28 TUBB4A VASP VHL YWHAZ ZNF331 ZNF579
Entrez ID		90480	3164
HPRD ID		05519	00744
Ensembl ID		ENSG00000179271	ENSG00000123358
Uniprot IDs		Q8TAE8	A0A024R126 F5GXF0 P22736 Q6ZMM6
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K	2QW4 3V3E 3V3Q 4JGV 4KZI 4KZJ 4KZM 4RE8 4REE 4REF 4RZE 4RZF 4RZG 4WHF 4WHG 6KZ5 6LC1
Enriched GO Terms of Interacting Partners?
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