GADD45GIP1 and TFIP11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GADD45GIP1	TFIP11
Description		GADD45G interacting protein 1	tuftelin interacting protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Ribosome	Chromosome, Telomeric Region Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Nuclear Speck Extracellular Matrix U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Cell Cycle	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome RNA Processing Biomineral Tissue Development Negative Regulation Of Protein-containing Complex Assembly Protection From Non-homologous End Joining At Telomere Negative Regulation Of Protein Binding Negative Regulation Of DNA Ligase Activity Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		62 interacting genes: ANKRD28 APP AR BPIFA1 CADPS CARD10 CBY2 CCNC CEP70 CSNK2B DVL3 EAF1 ENKD1 EXOSC4 FBXO7 GADD45A GADD45B GADD45G GAS8 GEM GOLGA2 GOLGA6A GOLGA6L9 GPRASP2 HMG20A IKBKG KANK2 KIFC3 KRT27 KRT31 KRT34 KRT40 LDOC1 LRRC73 LZTS2 MAGEA11 MAGEA6 MBD3 MIPOL1 MKRN3 MRPL38 MTUS2 MYG1 MYO15B NFKBID NR4A1 NTAQ1 NUTM1 OIP5 PBX4 PICK1 PNMA1 PRDM6 PSMB1 RBM11 SPTA1 TFIP11 TRAF1 TRIM27 UPF2 WWP2 ZRANB1	234 interacting genes: AARD ABI2 ABLIM3 AIMP2 ANKRD11 AP1M1 ARHGEF9 ARMC7 ARMCX1 ARNT2 ATP5PO ATPAF2 AXIN1 BAZ2B BCL6 BHLHA9 BMF BRD1 BYSL C1orf109 C2CD6 CARD9 CAVIN3 CBX8 CCDC102B CCDC116 CCDC120 CCDC121 CCDC13 CCDC146 CCDC187 CCDC196 CCDC42 CCDC57 CCDC6 CCDC68 CCDC96 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CDKN1A CDR2L CENPU CEP57 CEP57L1 CEP95 CFAP206 COQ8A COX5B CT55 CWF19L2 DAXX DDX25 DES DGCR6 DISC1 DPPA3 DTNB EAF2 EIF3A EIF3D ENOX2 EPM2AIP1 EXOC3L1 EXOC8 EXOSC5 FAM13C FAM156A FAM161A FAM161B FAM50B FAM81A FAM90A1 FANCG FGA GADD45GIP1 GAS2L2 GCC1 GCFC2 GEM GFAP GNG4 GOLGA1 GOLGA2 GPS2 GRAP2 GSE1 HAUS1 HDAC4 HIP1R HMG20B HOOK1 HSF2BP IKBIP IL16 IMP3 JRK KANK2 KANSL1 KAT5 KDM1A KIF3C KIF9 KIFC3 KIZ KRT1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5 LCA5L LENG1 LIN37 LMNB2 LMO1 LMO2 LMO4 LSM3 LSP1P3 LYSMD1 MAB21L2 MCM7 MDM2 METTL17 MFAP1 MKRN3 MRPL11 MTFR2 MXD3 MYO15B MYOM1 NDC80 NDE1 NDN NEK6 NFKBID NFU1 NSMF NUP88 ODAD3 OIP5 PBX3 PBX4 PCM1 PDE4DIP PHF1 PIBF1 PICK1 PKN3 PLK4 POLL POLR1C POM121 PPFIA3 PPP1R16A PPP1R16B PPP1R18 PRPF31 PSMA4 PSMC5 PSTPIP1 PTCD1 RCOR3 RHNO1 RIN1 RNF6 RRP7A RUNX1T1 RXRB S100P SAP30BP SCNM1 SFR1 SGF29 SH2D4A SH3GLB1 SHANK3 SMARCB1 SMARCE1 SNAPIN SNRPB SNW1 SNX20 SNX32 SOGA1 SPG21 SSX2IP STRA8 STRN SYCE1 TBC1D30 TBRG4 TCAF1 TDP2 TFPT THAP7 THAP8 TNNT1 TP53 TRAF3IP3 TRAPPC4 TRIM45 TRIML2 TSC1 TSG101 TSGA10IP TSHZ2 TSHZ3 TSPYL4 TUFT1 TXLNA TXN2 UBTFL1 USP2 USP6 USP7 VPS37C VPS39 WAC WASHC3 ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZNF572 ZNF587 ZNF777 ZSCAN12
Entrez ID		90480	24144
HPRD ID		05519	11628
Ensembl ID		ENSG00000179271	ENSG00000100109
Uniprot IDs		Q8TAE8	A0A024R1I7 Q9UBB9
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K
Enriched GO Terms of Interacting Partners?
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