PHLDB2 and FLNC

Number of citations of the paper that reports this interaction (PubMedID 12376540)
22

Data Source:
HPRD (in vitro, in vivo)

		PHLDB2	FLNC
Description		pleckstrin homology like domain family B member 2	filamin C
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Cell Leading Edge Intermediate Filament Cytoskeleton Basal Cortex	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Cytoskeletal Protein Binding Ankyrin Binding Actin Filament Binding
	Biological Process	Microtubule Cytoskeleton Organization Regulation Of Gastrulation Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis	Actin Cytoskeleton Organization Muscle Cell Development
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Cognitive performance ( 20125193) Crohn's disease-related phenotypes ( 25557950) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 30046033 32439900)	Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		5 interacting genes: CLK1 FLNC USP7 YWHAG YWHAQ	35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2
Entrez ID		90102	2318
HPRD ID		06611	00018
Ensembl ID		ENSG00000144824	ENSG00000128591
Uniprot IDs		Q86SQ0	Q14315 Q59H94
PDB IDs			1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?