CCDC120 and FCHSD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC120	FCHSD2
Description		coiled-coil domain containing 120	FCH and double SH3 domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Centriole Growth Cone Centriolar Subdistal Appendage	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	Protein Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Protein Localization Microtubule Anchoring At Centrosome	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS			Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 33272962 26663301)
Interacting Genes		106 interacting genes: AKAP8L ARID5A ATP23 BCAS2 BHLHB9 BLZF1 BRCA1 C1orf109 CADPS CALCOCO2 CCDC102B CCDC13 CCDC136 CCDC57 CCDC85B CDR2 CEP170P1 CEP55 CKS1B CNFN COG6 CTBP2 CYSRT1 CYTH1 CYTH2 CYTH3 CYTH4 DAZAP2 EFHC2 EIF3F FCHSD2 FOS FOSL1 FSD2 GOLGA2 GOLGA6L9 HNRNPH1 HOMER3 HOXA1 HSF2BP IFT88 IHO1 INTS11 KASH5 KRT15 KRT31 KRT34 KRT35 KRT38 KRT40 KRTAP13-3 KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMNA LMNB2 LMO4 LZTS1 MAGED1 MDFI MED11 METTL27 MID2 MIIP MIPOL1 MKRN3 MRPL38 MTUS2 MYOG NCK2 NEK6 NOTO NXF1 PKP2 PLA2G10 PLAGL2 PLEKHG4 POU2AF1 PRDM6 RABEP1 RBPMS RERE RINT1 RUSC1 SFI1 SMARCB1 SORBS3 SPAG8 STX11 TFIP11 TLE5 TP53BP1 TRAF1 TRIM42 TRIM55 TRIM63 TRIP6 TSC1 TSGA10IP USHBP1 ZDHHC17 ZIM2 ZMAT5 ZNF648 ZRANB1	53 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE2A PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587
Entrez ID		90060	9873
HPRD ID		06595	13321
Ensembl ID		ENSG00000147144	ENSG00000137478
Uniprot IDs		Q96HB5	O94868
PDB IDs			2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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