FCHSD2 and LCA5L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCHSD2	LCA5L
Description		FCH and double SH3 domains 2	lebercilin LCA5 like
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft	Axoneme
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding
	Biological Process	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Intraciliary Transport
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 33272962 26663301)	Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30224653) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		53 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE2A PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587	22 interacting genes: B3GALT5-AS1 CCDC136 CCDC197 DSCR8 EXOSC5 FCHSD2 IKBIP KRT75 KRT76 KRT80 KRT81 NMI PBXIP1 PRPH RIPPLY3 SUV39H2 SYCE1L TFIP11 TPM3 TSGA10IP ZDHHC17 ZGPAT
Entrez ID		9873	150082
HPRD ID		13321	10742
Ensembl ID		ENSG00000137478	ENSG00000157578
Uniprot IDs		O94868	O95447
PDB IDs		2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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