SAPCD2 and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		SAPCD2	RALBP1
Description		suppressor APC domain containing 2	ralA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Bicellular Tight Junction Apical Plasma Membrane Apical Junction Complex Apical Cortex	Spindle Pole Nucleus Mitochondrion Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Positive Regulation Of Cell Population Proliferation Regulation Of Establishment Of Planar Polarity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex	Positive Regulation Of Protein Phosphorylation Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways			CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494)	LDL cholesterol ( 30275531)
Interacting Genes		13 interacting genes: ATF4 BFSP2 C1orf109 CYSRT1 EXOC7 GMNN GPRASP2 KRT3 KRTAP1-3 MDFI RALBP1 USHBP1 VCL	46 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		89958	10928
HPRD ID		12943	09013
Ensembl ID		ENSG00000186193	ENSG00000017797
Uniprot IDs		Q86UD0	Q15311
PDB IDs			2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?
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