RALBP1 and CCDC136

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RALBP1	CCDC136
Description		ralA binding protein 1	coiled-coil domain containing 136
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Mitochondrion Cytosol Plasma Membrane Membrane	Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Acrosome Assembly Spermatogenesis Single Fertilization
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		46 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	138 interacting genes: ABT1 AQP1 ASB7 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 C21orf58 CARD9 CBX8 CCDC120 CCDC13 CCDC146 CCDC185 CCDC187 CCDC6 CCHCR1 CDC5L CDK2AP1 CEP57 CEP57L1 CEP95 COIL CWF19L2 DDX6 DISC1 DTNB DYNC1I2 ENKD1 FAM107A FAM161A FAM161B FAM50B FLYWCH1 GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B HOXB5 ISCU JAKMIP2 JMY JRK KANSL1 KAT5 KIF5B KIFC3 LCA5L LENG1 MAGEB4 MBD1 MBD3L2 MCRS1 MOS NDC80 NDN NEBL NEK6 NME7 NOP53 ODAD3 PDLIM5 PIBF1 PKN1 PKN2 POGZ PPP1R18 PRPF18 PRPF3 PRPF31 PRR35 PSMA1 PSMC5 PSMD9 RAB33A RAB33B RALBP1 RASAL3 RASSF8 SCNM1 SDHAF1 SHFL SMARCA2 SMARCE1 SYT6 TBRG1 TCEA2 THAP7 TNNT1 TRAF3IP3 TSGA10 TSGA10IP TSPYL1 TXLNA UBQLN4 UBTFL1 USP2 WT1 ZBTB24 ZBTB38 ZBTB47 ZC2HC1C ZFP1 ZFYVE26 ZNF124 ZNF20 ZNF223 ZNF230 ZNF250 ZNF264 ZNF329 ZNF35 ZNF408 ZNF417 ZNF440 ZNF490 ZNF497 ZNF564 ZNF572 ZNF580 ZNF581 ZNF587 ZNF599 ZNF648 ZNF669 ZNF670 ZNF688 ZNF696 ZNF774 ZNF777 ZNF785 ZNF835 ZNF837 ZSCAN26
Entrez ID		10928	64753
HPRD ID		09013	10887
Ensembl ID		ENSG00000017797	ENSG00000128596
Uniprot IDs		Q15311	A0A024R758 Q96JN2
PDB IDs		2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?
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