SYNJ1 and CLTA

Number of citations of the paper that reports this interaction (PubMedID 12057195)
71

Data Source:
BioGRID (proximity labelling technology, pull down)

		SYNJ1	CLTA
Description		synaptojanin 1	clathrin light chain A
Image
GO Annotations	Cellular Component	Cytosol Microtubule Vesicle Membrane Membrane Coat Clathrin Coat Of Coated Pit Terminal Bouton Perinuclear Region Of Cytoplasm Synaptic Membrane Parallel Fiber To Purkinje Cell Synapse Presynapse	Spindle Cytosol Plasma Membrane Membrane Clathrin Coat Clathrin Vesicle Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Synaptic Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Endolysosome Membrane Clathrin-coated Endocytic Vesicle Clathrin Complex Presynaptic Endocytic Zone Membrane Postsynaptic Endocytic Zone Cytoplasmic Component
	Molecular Function	RNA Binding Phosphatidylinositol-3-phosphatase Activity Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein C-terminus Binding SH3 Domain Binding Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity Protein-containing Complex Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity EH Domain Binding	Molecular_function Structural Molecule Activity Protein Binding Clathrin Heavy Chain Binding Peptide Binding Protein-containing Complex Binding GTPase Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Neurotransmitter Transport Brain Development Learning Positive Regulation Of Gliogenesis Synaptic Vesicle Priming Synaptic Vesicle Uncoating Response To Retinoic Acid Response To Cytokine Phosphatidylinositol-3-phosphate Biosynthetic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Metabolic Process Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Positive Regulation Of Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Synaptic Vesicle Transport Membrane Organization Positive Regulation Of Endosome Organization	Intracellular Protein Transport Cell Cycle Clathrin Coat Assembly Cell Division Clathrin-dependent Endocytosis
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of IP2, IP, and Ins in the cytosol Synthesis of IP3 and IP4 in the cytosol Clathrin-mediated endocytosis	Entry of Influenza Virion into Host Cell via Endocytosis Retrograde neurotrophin signalling Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Lysosome Vesicle Biogenesis Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance
Drugs
Diseases
GWAS		Platelet reactivity in response to clopidogrel treatment ( 32472697)	Bipolar disorder (inflammation and infection response interaction) ( 25781172) Bisphosphonate-associated atypical femoral fracture ( 31006051)
Interacting Genes		25 interacting genes: AMPH AP2A1 AP2M1 BIN1 CDK5 CLTA CLTC EPHB2 EPS15 FNBP4 GRB2 ITSN1 LRRK2 PACSIN1 PACSIN2 PACSIN3 PPP3CA SH3BP1 SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SH3KBP1 SORBS2 VPS26C	10 interacting genes: CLTC EGFR HIP1 HIP1R HSPA8 IFT57 MAP1LC3B RGS2 SHANK3 SYNJ1
Entrez ID		8867	1211
HPRD ID		09182	00351
Ensembl ID		ENSG00000159082	ENSG00000122705
Uniprot IDs		A0A0D9SGJ6 B9EGN3 C9JFZ1 J3KQV8 O43426 Q05CZ1	C9J8P9 P09496
PDB IDs		1W80 2DNR 2VJ0 7A0V	6E5N
Enriched GO Terms of Interacting Partners?
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