AKAP4 and KDM6A

		AKAP4	KDM6A
Description		A-kinase anchoring protein 4	lysine demethylase 6A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton CAMP-dependent Protein Kinase Complex Z Disc Motile Cilium Sperm Fibrous Sheath Perinuclear Region Of Cytoplasm Sperm Connecting Piece Sperm Midpiece Sperm Principal Piece Sperm End Piece	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex
	Molecular Function	Protein Binding Protein Kinase A Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Chromatin DNA Binding Histone Demethylase Activity Metal Ion Binding Dioxygenase Activity Histone H3-tri/di-methyl-lysine-27 Demethylase Activity
	Biological Process	Signal Transduction Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Protein Localization Flagellated Sperm Motility Motile Cilium Assembly Establishment Of Protein Localization	Chromatin Remodeling Heart Development Regulation Of Gene Expression Histone H3-K4 Methylation Histone H3-K27 Demethylation
Pathways			HDMs demethylate histones Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: AKAP3 FSIP1 FSIP2 KDM6A PRKAR1A PRKAR2A PRKAR2B	19 interacting genes: AKAP4 BMP15 CREBBP ELK1 GSC2 H3-4 H3C1 H3C14 HSD17B10 MAGED2 MEOX2 MTDH NKX2-5 RBM3 SMAD9 SRF TBX5 TLE1 ZNF157
Entrez ID		8852	7403
HPRD ID		02173	02131
Ensembl ID		ENSG00000147081	ENSG00000147050
Uniprot IDs		A0A384MQY7 Q5JQC9	A0A087X0R0 A0A6Q8PFK0 B4E0L8 B7ZKN1 B7ZKN5 B7ZKN6 E1U0S6 F5H5V6 F5H6S1 F8W8R6 O15550 Q59HG3 Q86TD1
PDB IDs			3AVR 3AVS 6FUK 6FUL
Enriched GO Terms of Interacting Partners?
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