TNFRSF10C and MGST1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNFRSF10C	MGST1
Description		TNF receptor superfamily member 10c	microsomal glutathione S-transferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Anchored Component Of Membrane	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding
	Biological Process	TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process	Response To Xenobiotic Stimulus Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Glutathione Transport Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands	Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation
Drugs			Glutathione Glutathione disulfide
Diseases
GWAS		Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte count ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)	Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bell's palsy ( 33602968) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Visceral fat ( 22589738)
Interacting Genes		34 interacting genes: APOA1 AQP6 ARL13B ASZ1 CD79A COQ9 CREB3L1 CXCL14 CYB5R3 DNAJC1 ERGIC3 FAM209A GPR152 GPR37L1 KCNJ6 KCNK5 LMNA LRSAM1 MGST1 MRPS18B PDZK1IP1 RAP1A RFLNB SGTA SLC27A6 SLC30A4 SRPK1 SRPK2 STOM SYAP1 TMEM45B TMEM80 TNFSF10 ZHX1	8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP
Entrez ID		8794	4257
HPRD ID		04681	00705
Ensembl ID		ENSG00000173535	ENSG00000008394
Uniprot IDs		O14798	A0A024RAX2 P10620
PDB IDs
Enriched GO Terms of Interacting Partners?
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