MGST1 and VIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGST1	VIP
Description		microsomal glutathione S-transferase 1	vasoactive intestinal peptide
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell	Extracellular Region Neuron Projection Perikaryon
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding Peptide Hormone Receptor Binding
	Biological Process	Response To Xenobiotic Stimulus Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Glutathione Transport Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification	Positive Regulation Of Endothelial Cell Proliferation G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Body Fluid Secretion Learning Or Memory Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epinephrine Secretion Regulation Of Protein Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Potassium Ion Transport Positive Regulation Of Protein Catabolic Process Epinephrine Secretion MRNA Stabilization Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Sensory Perception Of Pain Positive Regulation Of Penile Erection Prolactin Secretion
Pathways		Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation	G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Glutathione Glutathione disulfide
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bell's palsy ( 33602968) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Visceral fat ( 22589738)	Body mass index ( 26426971) Chronotype ( 30696823) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600)
Interacting Genes		8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP	11 interacting genes: CTNNA3 MEOX2 MEP1A MGST1 MME PRICKLE1 SGTA UBQLN2 UBQLN4 VIPR1 VIPR2
Entrez ID		4257	7432
HPRD ID		00705	15950
Ensembl ID		ENSG00000008394	ENSG00000146469
Uniprot IDs		A0A024RAX2 P10620	P01282
PDB IDs			2RRH 2RRI
Enriched GO Terms of Interacting Partners?
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